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Tanaka T, Higashijima Y, Wada T, et al
Decreased prevalence of diabetes in marijuana users: cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) III
Using a library of immunoassays and a sensitive MS-based platform [20], we have identified fragment(s) identical to the anticipated sequences that would be produced by endoproteolytic cleavage of GLP-1(936)NH 2 by the NEP 24.11 enzyme [11], including DVSSYLEGQAAKE [GLP-1(1527)NH 2 ] and FIAWLVKGR-NH 2 [GLP-1(2836)NH 2 ], consistent with cleavage of GLP-1 in the mid region of the peptide (EGTFTSDVSSYLEGQAAKE-FIAWLVKGR)
It does not activate the hGH receptor or raise IGF1 levels, and it has no meaningful effect on blood glucose or insulin sensitivity
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