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The fundamental attributes of hydrogels lie in their three-dimensional hydrophilic polymer networks, which exhibit biocompatibility, biodegradability, and high drug-loading capacity, enabling on-demand drug release in response to environmental stimuli (e.g., pH and temperature) (Mathew et al., 2018)
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It has been shown by various methods (subcellular fractionation, electron and fluorescence microscopy) that in the absence of insulin in these tissues, most (approximately 95%) of GLUT4 is located intracellularly
Role of the essential metalloid in health
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It helps maintain mitochondrial activity, glucose oxidation and fat metabolism in skeletal muscle and heart tissue, supporting energy availability, physical stamina and normal muscle response to exercise
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