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Alcohol is a diuretic, which means it makes your kidneys flush out more water than you're taking in

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Jul 2011;6(7):1526-1532

The best option for oral supplementation is taking liposomal glutathione on an empty stomach

The Premature Infant Pain Profile score (PIPP score) was lower in 30 infants treated with common sedation plus melatonin during intubation and mechanical ventilation than in those treated with common therapy alone 115

In other words, Weaver says, heed the advice you knew about long before products like these hit the market: Dont drink on an empty stomach.