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TL;DR: In a large sample of US Veterans, GLP-1 drugs were associated with reduced risk of substance use and psychotic disorders, seizures, neurocognitive disorders (including Alzheimers disease and dementia), coagulation disorders, cardiometabolic disorders, infectious illnesses and several respiratory conditions, but increased risk of gastrointestinal issues, hypotension (low blood pressure), and some kidney-related conditions
His significant contributions to sports medicine have been recognized at the NFL Hall of Fame
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Starting from an average weight of 248.5 pounds, patients experienced dramatic improvements beyond weight loss
In the absence of population-specific data, clinical use should be accompanied by vigilant monitoring for class-wide effects (particularly gastrointestinal symptoms) and agent-specific concerns, with dose titration individualized to tolerability
Cryo-EM methods Negative staining transmission electron microscopy The homogeneity of the protein before structural determination was assessed by negative staining electron microscopy
