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WHERE ARE B12 SHOTS ADMINISTERED
Although 40,000 g is a significant amount for the body, its a small amount to the eye
UK obesity guidance including NICE CG189 (Obesity: identification, assessment and management) and NICE PH53 (Weight management: lifestyle services for overweight or obese adults) does not recommend vitamin B12 supplementation as a weight management intervention
Regulatory note: The FDA added injectable GHK-Cu to a high-risk compounded substance list in September 2023
Hydroxocobalamin has an excellent safety profile, as excess B12 is readily excreted in urine
For physique athletes and performance-driven individuals, this SIRT1 pathway activation means more fat burned, more muscle spared, and a higher energy ceiling during both cutting and maintenance phases
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