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But previous studies have shown that increased citrulline directly binds to JAK2 and inhibits JAK2-STAT1 signalling ( 1,5-AG is one of the main polyol sugars in the human body, is mainly derived from food and is hardly synthesized by the human body (Yamanouchi and Akanuma, 1994)

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Thus, our data indicate that paraxanthine increases BDNF levels to a greater extent than caffeine, which may underlie its cognitive-enhancing effects in both young and old animals

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NAPQI is a reactive metabolite formed by the action of cytochrome P450 on paracetamol (acetaminophen)