myostatin inhibitor glp 1 GDF8 and activin A blockade protects against GLP-1–induced muscle loss while enhancing fat loss in obese male mice and non-human primates Balancing weight and muscle loss

Gejl M, Gjedde A, Egefjord L, Moller A, Hansen SB, Vang K, et al

Patients should bring their full medical history and medication list to any consultation so the risk discussion is specific, not generic

Novo Nordisk estimated the figure at 1.5 billion doses over six months

We included patients who had been treated with an SGLT2i or GLP-1 RA for at least 6 months and analysed the efficacy, safety and cardio-renal outcomes 5 years after initiation of therapy

Most GLP-1 drugs are self-administered via injection, either once per week or daily, although one brand, Rybelsus, is available in pill form

Rex DK, Ahnen DJ, Baron JA, Batts KP, Burke CA, Burt RW et al (2012) Serrated lesions of the colorectum: review and recommendations from an expert panel