GLP-1 medications mimic the natural action of the gut hormone glucagon-like peptide-1 (GLP-1), which regulates blood sugar levels and appetite
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Mechanism of Action for Weight and Metabolic Regulation Cagrilintide reduces food intake, delays gastric emptying, and modulates glucagon secretion through coordinated receptor agonism that recreates and amplifies key amylin pathways for weight and glucose control
Recognizing this potential in the fight against obesity, the FDA approved GLP-1 injections as a weight loss treatment in 2022
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Red and yellow circles indicate localized GLP-1 receptor mRNA transcription Activation of incretin receptors initiates a cascade of neuroprotective effects: Improved brain insulin signaling, correcting neuronal energy deficits