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It aids in controlling blood sugar levels by encouraging the release of insulin when blood sugar is elevated
Mechanistic work has demonstrated that GLP-1R activation can restore homeostasis in microglia and astrocytes 1620 , reduce oxidative stress 2124 , increase blood-brain barrier integrity 19,25,26 , improve vascular health 21,27 , and attenuate peripheral inflammation 21,2831
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Subject demographics (for example: age, sex, self-identified race), lab values (for example: HbA1c, BMI, liver enzymes), and some medication information (GLP-1 M, other drugs used to treat T2D, and NSAIDs) and presence or absence of diabetes-associated complications (for example: chronic kidney disease, cardiovascular disease) were extracted as prediction features
Over five years, non-GLP-1 spending increases by $6,800, or 30 percent of the amount spent on GLP-1s
