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Patients already on metformin HCl (N=431) at a dose of at least 1500 mg per day were randomized after completing a 2-week single-blind placebo run-in period

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But there are controversial reports regarding the effect of fatty acids oxidation on glucose metabolism

The GLP1R rs6923761 variant and GIPR rs1800437 variant are associated with differences in receptor sensitivity and signaling strength

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