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139 Additionally, GLP-1RAs have been shown to enhance motor function and prolong survival in amyotrophic lateral sclerosis models, reduce neuronal degeneration, improve behavioral outcomes in Huntingtons disease models, and confer neuroprotection following traumatic brain injury and stroke by mitigating inflammation, reducing cerebral edema, and promoting neurological recovery

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In many cases, the answer lies in a mix of side effects, cost, and patient expectations

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In certain groups, these difficulties cause slow adoption and affect patient adherence