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Anagliptin, a DPP-4 inhibitor, suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction and attenuates atherosclerosis in male apo E-deficient mice
Eligibility also requires absence of personal or family history of medullary thyroid carcinoma, recent pancreatitis, or active diabetic retinopathy requiring concurrent treatment
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Modulations of signaling pathways related to cellular re-organization, extracellular matrix dynamics, and epithelial integrity are observed among experimental systems
Broadening Use in Obesity and Cardio-Metabolic Treatment Ozempic is no longer confined to type 2 diabetes care, as physicians increasingly prescribe it for obesity and cardiovascular risk reduction