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Users of semaglutide often report diminished hunger, quicker satiation during meals, reduced cravings for caloric-dense foods, increased energy levels for physical activities, and notable improvements in blood pressure, cholesterol, and glucose levels
As GLP-1 medications can produce significant and sustained weight loss, improvements in body weight and metabolic health likely play a role in the observed risk reduction
As a GLP-1 receptor agonist and GIP receptor agonist, it imitates hormones that regulate glucose metabolism
NICE recommends graded exercise programmes tailored to individual pain and fatigue levels, dietary interventions with dietitian support, psychological therapies such as CBT, and alternative medications like orlistat
Constipation puts increased pressure on the bladder, which can lead to incomplete emptying
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