tirzepatide and exercise Can Help You Lose Weight? Tirzepatide for Medical Weight Loss

Loss of muscle can slow metabolism and make further weight loss more difficult

GIP is the most abundantly secreted incretin hormone following nutrient intake, released from duodenal and jejunal K-cells in response to fat and carbohydrate ingestion yet its role in metabolic regulation beyond insulin secretion has historically been undercharacterised relative to GLP-1

LeBlanc GA et al

Journal of Thoracic and Cardiovascular Surgery 161(4):1497-1504.e2, 2021

This can be moderate intensity exercise, such as walking, swimming, cycling or dancing

Over-the-counter medications for constipation Over-the-counter (OTC) laxatives and stool softeners can relieve semaglutide constipation quickly, and theyre affordable and easy to get at most pharmacies