GLP-1s have been used to treat Type 2 Diabetes since 2005
The clinical evidence This question can be answered more clearly than for most drug side effects, because the data here are unusually good
Du J, Zhu Y, Yang X, Geng X, Xu Y, Zhang M, et al
Circulation 107(3):499511
Frequently asked questions Can GLP-1 medications prevent breast cancer
This evolution in treatment highlights an urgent need for evidence that moves beyond weight loss alone to examine long-term cardiometabolic health, quality of life, and durability of treatment effects. Concerns about youth on GLP-1 According to Messiah, GLP-1 medications have demonstrated meaningful benefits for adolescents living with obesity, including substantial weight reduction and improvements in obesity-related conditions such as type 2 diabetes and hypertension, but she underscores that drugs need to be prescribed appropriately and accompanied by ongoing medical supervision