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When cells are exposed to oxidative and/or electrophilic stress, KEAP1 thiol residues are directly modified, which inactivates the ubiquitin E3 ligase activity of KEAP1-CUL3 complex, leading to stabilization of NRF2
She also appreciated its unscented formula, user-friendly pump packaging, and the fact that it provided enough hydration to occasionally skip moisturizer
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10.1097/TP.0000000000001691 10
When taken as a supplement, the goal is typically to replenish or support the levels your body is already trying to maintain
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