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doi: 10.1016/j.taap.2024.116883 125 ShafiSKhuranaNGuptaJ

Mechanism Differences These medications do not work identically

Knowing what to expect and how to manage these effects makes the transition smoother

The most common problems are with the stomach and intestines

However, due to concerns for safety, quality, and effectiveness of compounded GLP1RAs, the American Diabetes Association (ADA) has issued guidance recommending switching individuals to different FDA-approved medications to achieve and maintain individualized glucose-lowering, weight management, and/or cardiovascular and kidney risk reduction goals when supply or access is limited [75]

Discard the vial and start over