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Serious or severe skin reactions were infrequent in the trial populations studied to date
Because many previous reports demonstrated that hypertension alone induces a shift from fatty acid oxidation toward increased glucose utilization in cardiac muscle, hypertension complicated with HFpEF might have additive effects on energy metabolic failure in heart
Ethics statement All experimental procedures were approved by the Ethical Committee of the Faculty of Veterinary Medicine of the University of Ghent, Belgium (approval number EC2011-113) and carried out in accordance with the approved guidelines and regulations
doi: 10.4239/wjd.v14.i4.424
Photo: Europol
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