The largest dataset based on whole-body counting is provided by Heinrich (Heinrich, 1967), who studied doses up to 100,000 g
Deficiency is particularly common in elderly people, because the ability to absorb vitamin B12 can decrease with age ( Other people at risk of deficiency include those who have had intestinal surgery, including weight loss surgery
The bodys ability to absorb vitamin B12 is reduced with increasing age
Some studies suggest that sublingual cyanocobalamin (131-133) and sublingual methylcobalamin (134, 135) are effective at increasing vitamin B 12 status
(More information) Vitamin B 12 is essential for the preservation of the myelin sheath around neurons and for the synthesis of neurotransmitters
When these connective tissues are stretched or torn, it can destabilize the joint they are attached to causing pain, laxity and improper movement of the joint