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Both semaglutide and liraglutide are MHRA-approved and are supported by NICE technology appraisals TA875 for semaglutide and TA664 for liraglutide which set out specific eligibility criteria

Baseline labs: panel selected based on indication

Because the cypionate ester permits a lower injection frequency, hormonal peaks are blunted, which may reduce the incidence of estrogen-related headaches and cyclic mastalgia observed with short-acting formulations, although inter-individual variation remains and careful titration is still recommended to optimize benefit-risk balance

This location can have more fat than other areas on the body and may not be the best area if you have excess body fat

Increases in heart rate were observed, consistent with semaglutide therapy

Regulatory Status Research Use Only