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The data showed a modestly reduced risk of depression with GLP-1RAs when compared with DPP4is and a negligible difference in depression risk between GLP-1RAs and SGLT2is
While these cardiovascular benefits may be related to multiple mechanisms, including weight loss, the specific contribution of visceral fat reduction has not been definitively established
Key finding: Systematic review confirmed accelerated healing across tendon, ligament, muscle, and bone injury models , with proposed mechanisms including VEGF upregulation and inflammatory modulation
doi: 10.1210/clinem/dgz047 85 NahraRWangTGaddeKMOscarssonJStumvollMJermutusLet al
