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These are predominantly present in the first eight to twelve weeks and resolve for the majority of participants after the body has adjusted to the compounds effects on gastric motility

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However, fatigue is listed as a common adverse reaction in FDA labeling, particularly for Wegovy, occurring through indirect mechanisms such as caloric restriction and gastrointestinal effects rather than direct sedation

Ultimately, they reflect the fact that levels of drug exposure will vary based on a universal one-size-fits-all dosing regimen

However, there are also less common events associated with them

The widely popular medication briefly made manufacturer Novo Nordisk Europes most valuable firm