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The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
This condition can also be exacerbated by stress and food allergies or intolerances
Reducing the pressure placed on the jaw during sleep can help relieve muscle tension and decrease the likelihood of waking up with a headache
But mitochondria can also the source of a lot of oxidative stress, which has been implicated in cancer, diabetes, metabolic disorders, and heart and lung diseases, among others
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