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However, accumulating ChIP-seq data indicates that NRF2 predominantly binds intronic or distal intergenic regions (Malhotra et al, 2010

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[6] Release of GST-A1 as an indication of cellular necrosis [edit] Increases in serum and urinary GST-A1 have been found in association with hepatocyte and renal proximal tubular necrosis respectively, and have potential for monitoring injury to these tissues

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