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This idea was further supported when similar phenotypes were observed across ferroptosis-sensitive and ferroptosis-resistant cancer cell lines (Extended Data Fig

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However, autophagy was activated in GBM cells exposed to PURE G4 -LA 12 -anti- GLS1 -siRNA, suggested by the increased levels of autophagy related 12 (ATG12) protein, in both cell lines at 72 h (Fig

sGC, soluble Guanylate Cyclase