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JAK-STAT pathway alterations impair immune homeostasis by affecting immune cell development and function
The use of nebulized GSH was used in a small but randomized pilot trial of patients cystic fibrosis, and found to improve several clinical indicators, such as peak flow
When activated also through 5-HT2A receptors by the increase of 5-HT in peripheral blood or by the binding of EBERs to TLR3, platelets bind to fibrinogen, causing enhancing aggregation and coagulation processes [279, 309]
Funding This work is supported by the European Union's-Next Generation EU'' program through the Italian PRIN 2022M4C2, Investimento 1.1-grant n
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