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Separate sections were immunostained for PC1/3 using a monoclonal anti-mouse antibody (Abcam, ab3532
Hyperglycemia has been shown to negatively regulate FoxO1 expression and paralleled loss of insulin content 22
Tirzepatide is sold under the name Mounjaro
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These include: nausea vomiting diarrhoea constipation stomach pain bloating dizziness low blood sugar, especially in people with type 2 diabetes Side effects are most likely to happen when starting treatment or after increasing your dose
It plays a key role in maintaining glucose homeostasis by increasing insulin secretion and reducing glucagon levels post-meal
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