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If levels climb high into normal range and symptoms resolve, continue the current protocol

doi:10.2147/CCID.S128339

Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels

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Because of this low oral bioavailability, clinical formulations of ALCAR must be dosed high enough to ensure that an adequate amount of the active compound survives the digestive process and reaches the blood-brain barrier

Leaky brain in neurological and psychiatric disorders: drivers and consequences