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There are several points of the TCA cycle that are critical for NRF2-regulated processes
When B12 dips too low, the symptoms can overlap surprisingly well with how some people feel on a new weight-loss regimen: Persistent fatigue and weakness Brain fog or memory changes Tingling or numbness in the hands and feet Constipation or other digestive changes That overlap is a big part of why the semaglutide-plus-B12 idea took hold in the first place
Its as if youre not even taking it. Patients should use an additional barrier method, and women who become pregnant should stop the GLP-1 medication immediately
doi: 10.1002/ana.21692 65 OldhamW
MOTS-c is a 16-amino-acid mitochondrial-derived peptide
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