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Fatigue, brittle nails, hair thinning, and low energy are among the early warning signs clinicians may notice when nutrient intake drops too low

Almeida OP, Ford AH, Flicker L

Symptoms of overmethylation can include: [23] Restless legs/pacing Hyperactivity High pain tolerance Histamine intolerance Sleep disorders Panic disorders Paranoia Insomnia Low libido ADHD Low motivation Depression Anxiety High levels of neurotransmitters (dopamine, norepinephrine, and serotonin) A high copper to zinc ratio Generally, undermethylation will result in symptoms more akin to depression and sluggishness, while overmethylation is usually linked to symptoms like hyperactivity and anxiety

Peptides most likely to be tested for are those associated with performance enhancement , especially in sports