In patients with obesity and heart failure with a preserved ejection fraction included in the STEP-HFpEF trial, semaglutide significantly reduced symptoms, improved physical limitations, and enhanced exercise functions compared to placebo (89)
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Due to alcohol-induced inhibition of B lymphocyte differentiation, patients with ALD experience a reduction in B lymphocytes, which are essential for humoral immune responses [91]
27 It has even been shown to counteract certain drug-induced neurotoxic effects (for instance, preventing catalepsy a Parkinson-like frozen state in rodents given specific neurotoxic drugs)
R.TsapasA.et al (2022)
Wettergren A, Wjdemann M, Holst JJ