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Peptides like those in GLOW are not FDA-approved for human use
The peptide exhibits consistent efficacy in models of acute and chronic injury regardless of administration route (intraperitoneal, oral, or local application), a unique characteristic distinguishing it from other growth factors that typically require localized delivery with carrier systems
Composition inconsistency: the amount of compound per unit can vary between batches
(PMC) A separate metabolism-focused paper reviewing human trial history makes a similar point: early signals of weight loss were not consistently reproduced in later studies, particularly when intensive diet/exercise protocols were included
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