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Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress
Bs team
10.1016/j.ejphar.2007.04.023 305 WangC.LiJ.LvX.ZhangM.SongY.ChenL.et al (2009a)
Biochemistry 9 , 50155023 (1970)
However, someone with a more severe deficiency might need to wait a little longer, possibly requiring multiple injections to replenish their B12 stores
They were only valid for a few months at a time
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