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En condiciones fisiolgicas normales, hasta aproximadamente el 90-98% del glutatin celular se encuentra en forma de GSH reducido, y un cambio hacia niveles ms elevados de GSSG se utiliza ampliamente como indicador de estrs oxidativo y deterioro de la salud celular

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3d), the pyranose glucoside is closer to the dicopper center, with its ether group interacting with CuB at a distance of 2.5 , and two hydroxyl groups forming hydrogen bonds with S361 and E326, which stabilizes the ligand binding

doi: 10.1016/j.molimm.2022.12.015 139 ZongZ

4a, e) and strengthen the metabolic parallel between GSH-deficient FoB and GSH-sufficient MZB