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For some people, semaglutide can take things too far

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[82] As a glucagon-like peptide-1 receptor agonist, semaglutide suppresses the release of glucagon by the liver which in turn lowers blood pressure

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In light of these findings, the College for Sexual and Reproductive Health (CoSRH) advises that women switch to a non-oral or barrier method of contraception for four weeks after initiation of tirzepatide, and four weeks after any dose change

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