all use must occur within a formally supervised clinical trial, following trial-specific protocols
One study that looked at the relationship between obesity in men and testosterone deficiency shows that testosterone therapy produces sustained weight loss without recidivism (reverting to previous weight)
When you lose weight, especially visceral fat, your bodys cortisol levels may decrease
None of that prevents melanocortin receptor pharmacology being a legitimate field, and MC1R signalling in cultured melanocytes is a reasonable thing to study
Santella C, Yin H, Hicks BM, Yu OHY, Bouganim N, Azoulay L
GLP-1 medications are used to promote weight loss