patients should be advised to seek immediate medical attention for severe, persistent abdominal pain Gallbladder disease : cholelithiasis and cholecystitis have been reported with GLP-1 receptor agonists [11] [22] Diabetic retinopathy complications : particularly in patients with pre-existing retinopathy who experience rapid improvement in glucose control Common adverse effects of Januvia include: Upper respiratory tract infections and nasopharyngitis Headache and gastrointestinal disturbances (though generally milder than with GLP-1 agonists) Rare but serious risks : acute pancreatitis, severe joint pain, hypersensitivity reactions, and bullous pemphigoid (a serious skin condition) When used together, there is a theoretical increased risk of gastrointestinal side effects , particularly nausea, as both medications influence gut hormone pathways

Learn More Ozempic A once-weekly injectable GLP-1 that is indicated for the treatment of Type 2 Diabetes.* Learn More Wegovy A once-weekly injectable GLP-1 indicated for the treatment of overweight and obesity
Oral Wegovy (Semaglutide Pill) For those who prefer oral medications, Oral Wegovy offers another convenient option
Receiving a refill signifies a commitment to another 3 months of membership dues
Avoid weight/obesity bias in deciding who should discontinue GLP-1RA therapy
Of these, the incretin hormone, glucagon-like peptide 1, is probably the most important