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In eczema, this balance collapses

This interaction enhances NF-B activation and nuclear translocation, allowing it to bind the promoter of the gene encoding Bcl-2, leading to the upregulation of this anti-apoptotic protein and the consequent inhibition of CytC release and apoptosis induction [49, 50]

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Clinically, IGF-1 and derivatives are used to treat patients who suffer from muscle wasting due to conditions like HIV, as well as patients with hormonal disorders [2]

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An investigation of apoptotic responses following adenovirus-mediated p53 gene delivery