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4.1

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Description

Mitochondrial dysfunction and metabolic reprogramming induce macrophage pro-inflammatory phenotype switch and atherosclerosis progression in aging

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CrAT deficiency leads to accumulating acetyl-CoA, which exerts an allosteric inhibiting effect on pyruvate dehydrogenase (PDH), a rate-limiting enzyme for pyruvate entry into the Krebs cycle

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No changes in electrocardiogram or worsening of liver or kidney function have been reported

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Two forms L-carnitine base and L-carnitine L-tartrate

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2010 : GHK-Cu 4000

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MAPK: mitogen-activated protein kinases

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