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In another study, both circulating DPP-4 levels and the amount released from adipocyte explants in vitro were found to be positively correlated with adipocyte size as well as with anthropometric parameters such as BMI, waist circumference and percent body fat (79)
In January 2025, regulators added warnings about severe gastrointestinal adverse reactions, acknowledging that the slowed gastric emptying mechanism can lead to far more serious consequences than initially disclosed
Despite this high prevalence and the progressive nature of the disease, therapeutic options remain limited
Cell Signal 51:1322
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