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In a seminal article published in 1889, Reginald H

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By prompting insulin production and lowering the release of glucagon, GLP-1s like semaglutide have been helping patients with type 2 diabetes regulate their blood sugar levels for more than 15 years

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The HbA1c reduction, as with other antihyperglycaemic agents depends largely on the patient population studied, the baseline glycaemic situation at the beginning of the observation and the concomitant therapy, including life-style intervention (12, 19, 21, 22)

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Microbiology 149, 20232030 (2003)

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