2,3 Those who switched to orforglipron from Wegovy were able to maintain previously achieved weight loss, with an average difference of 0.9 kg
The evidence is extremely weak for a genuine effect in this instance A useful remark in the accompanying editorial is Khouri et al showed a wide variability of results coming from disproportionality analyses, depending both on the method and model specifications, thus opening the door for a selective reporting of results
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Supplementary Table 5 TRUUST analysis of differentially expressed genes after 24 hours of BDG exposure in human monocytes