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2025;doi:10.1056/NEJMoa2413258

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Additionally, some patients report that certain injection sites may feel more sensitive at different times

A 29 gauge needle produces significantly less discomfort than a 25 gauge needle and is thin enough that most patients describe the sensation as a mild pinch rather than a sting

Serum ferritin levels can be used to differentiate the two diseases, since generally serum ferritin is reduced in iron deficiency anemia but not ACD (Weiss 2005)

The initial rapid response may stabilize into steady, incremental improvement