For symptom management of neuropathic pain, the American Academy of Neurology and American Diabetes Association guidelines recommend: First-line: Duloxetine or pregabalin (with appropriate renal dose adjustments) Alternative options: Gabapentin (with renal dose adjustments) or tricyclic antidepressants (with caution in older adults and cardiac disease) Topical treatments: Capsaicin 8% patch or lidocaine 5% patch for localized symptoms Avoid chronic opioid therapy due to limited evidence and safety concerns Non-pharmacological approaches including physical therapy, proper foot care, and pain psychology techniques provide additional benefit
Lower the risk of major cardiovascular events such as heart attack and stroke and cardiovascular death in adults with known heart disease and either obesity or overweight, alongside diet and exercise
Occasional palpitations without other symptoms might not be serious, but persistent or severe palpitations should prompt a medical evaluation
What semaglutide does differently Semaglutide is widely used for weight loss because of its effects on appetite regulation
These outcomes come from full-dose studies
About 20 minutes after the survey was submitted, Hims offered a prescription via text, and compounded semaglutide was on the way