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Nausea, vomiting, constipation, and diarrhea are described as dose-dependent, so the article treats the starting step as an acclimation period for the gut

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The recommended dose for children ranges between 50-100 mg per kg orally daily for up to one year

Some clinical trial data suggest that Tirzepatide at 7.5mg and higher doses may be associated with meaningful weight reduction in some patients