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At MetaVia, that question has become central to drug design

Coverage by Cigna, Blue Cross Blue Shield, Medicare, Medicaid, Aetna, and Amerigroup hinges on medical necessity and plan specifics

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After repeated administration, rats in the short-access paradigm exhibited lower daily and cumulative METH intake than saline controls, with this effect becoming apparent on the second day of treatment and continuing throughout the study, while LIR did not affect METH-taking behavior in the extended-access paradigm