Catch up quick: Companies were permitted to make compounded versions of Novo Nordisks semaglutide and Eli Lillys tirzepatide when the brand-name versions were in short supply
Mild for some, worse initially or after dose increases
Mulvihill EE, Varin EM, Gladanac B et al (2017) Cellular sites and mechanisms linking reduction of dipeptidyl peptidase-4 activity to control of incretin hormone action and glucose homeostasis
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Regulation of inflammatory and immune responses by GLP1-RAs A substantial body of research suggests that the GLP-1 signaling pathway plays a pivotal role in regulating the infiltration of various anti-tumor immune cells, including CD4 + T cells, neutrophils, NK cells, macrophages, and dendritic cells
Again and again, regulators said they could find little data on safety or effectiveness and raised concerns about risks of contamination, allergic reactions and quality control