The copper-binding tripeptide has been shown to stimulate collagen synthesis in fibroblast cell cultures, promote decorin and glycosaminoglycan production, and modulate expression of metalloproteinases (MMPs) involved in extracellular matrix remodeling in vitro
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The Nrf2 activation by hesperidin may have also contributed to reduced iron-induced oxidative stress in the mouse kidney
doi: 10.1124/mol.114.093096 60 TellegenA
The Food and Drug Administration (FDA) currently approves over 100 peptides
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