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For rheumatoid arthritis, they are not replacements for your DMARD or biologic but the 2025 research from centers like UCLA suggests they can be a powerful complement: less disease activity, fewer flares, lower inflammation markers, better cholesterol and blood sugar, and reduced cardiovascular risk sometimes even at low doses

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Theoretically, a low S-5-HT value would be expected to result from lack of its precursor tryptophan or disturbance in the two-step synthesis described above

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[56] In 2023, Australian band King Gizzard and the Lizard Wizard released a single titled "Gila Monster" from their album PetroDragonic Apocalypse , with the album's artwork featuring a Gila monster on its cover art and heavily within the album's concept narrative