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For off-label weight management, providers typically apply the same 30/27 thresholds used for Wegovy

The blood samples were collected in tubes containing EDTA (1.5 mg/mL blood), protease inhibitor cocktail (10 mL/mL blood

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While the anti-inflammatory properties of GLP-1 therapy are promising, clinicians should counsel patients that definitive evidence for direct joint pain relief independent of weight loss is lacking

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Phase 2 trial (48 weeks, obesity population) Published in the New England Journal of Medicine (Jastreboff et al.), this trial enrolled 338 adults with a body mass index of 30 or higher, or 27-30 with at least one weight-related condition